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Previously we released a report that stated that from a list of 300 current projects that are underway in the type 1 field, only 35 of them investigate a possible cure for type 1 diabetes. That number was small on its own, but after further analysis, we have confirmed that only 5 of them could potentially meet the JDCA’s definition of a Practical Cure.

As a reminder, our Practical Cure definition is:

•  For at least 1 year, a cure must:
–  Not require blood glucose monitoring beyond once a week
–  Not require carb counting
–  Not restrict a patient’s diet
–  Allow patients to sleep care free
–  Keep A1c levels between 6-7

•  A cure must be delivered through a treatment that:
–  If it is surgical, requires a full recovery of less than 72 hours
–  If it is pharmacological, requires no more than a reasonable pill and/or injection regimen

•  A cure, which may include a drug regimen,  must not have side effects or pose longer term risks greater than current complications of type 1

What this means is that only an extremely small percentage of donor contributions to the four major type 1 foundations is used to fund research in clinical trials that has the potential to deliver a Practical Cure. The vast majority of the money the JDRF, ADA, DRIF and Joslin raise through inspirational cure fundraisers does not go into fighting for a cure in our lifetime.

Read our full report here.

Some important conclusions will have to be made about where we are currently headed in the search for a cure based on this information.  But more significantly, we must think about how we can change this progress.

– Stoyan

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